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Published in Science Translational Medicine: Single-Cell Secretome Reveals Functional Profiles of Immune Cells in Hard-To-Treat Cancers

Cancer Immunology /

Cancer has long been one of the most challenging diseases to treat as traditional treatments, like chemotherapy and radiation, can be harsh on the body and are not always successful. However, recent advancements in the field of immunotherapy have improved anti-cancer treatments; one of the more promising immunotherapy approaches being Immune Checkpoint Blockade (ICB) therapy. […]

Published in Science Translational Medicine: Single-Cell Secretome Reveals Functional Profiles of Immune Cells in Hard-To-Treat Cancers Read More »

Revolutionizing Immunotherapy Research and Development With the New Opto® T Cell Profiling Workflow

Cancer Immunology /

Polyfunctional T cells, which produce multiple cytokines, are considered to be the most potent anti-tumor effector T cells. To find polyfunctional T cells in a heterogeneous sample, researchers must be able to characterize functional cytokine secretion and cytotoxicity at the single-cell level. However, most existing methods evaluate samples in bulk and are destructive endpoint assays,

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Bruker Cellular Analysis at PEGS Boston: Interrogating the Phenome at the Cutting Edge of Biotherapeutics

Events /

Bruker Cellular Analysis is looking forward to attending the upcoming PEGS Boston Summit from May 15-19. PEGS is the world’s largest gathering of protein engineering and biotherapeutics experts, and we are excited for the opportunity to meet with industry leaders and demonstrate how our groundbreaking platform is empowering researchers to leverage the full potential of

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Exploring the Phenome Across Discovery and Development: Single-Cell Research Featured at AACR 2023

Cancer Immunology /

We attended this year’s AACR meeting and wanted to thank everyone for such an incredible turnout and experience as we introduced Bruker Cellular Analysis to many of you for the first time. We had a great time speaking with so many amazing researchers that are enthusiastic about our technology, and loved to see all of

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Published in Nature Communications: Revealing the Transcriptomic Drivers of Highly Polyfunctional CAR-T Cells with Bruker Cellular Analysis’ Duomic Technology

Cellular and Regenerative Medicine /

While CAR-T therapies have been revolutionary in the fight against cancer, current FDA approvals for these therapies focus on targeting CD19 or BCMA in B-cell malignancies. Unfortunately, of the patients treated, only up to 50% maintain a sustained response in the long-term. Relapse can occur when cancer adaptively limits CD19 or BCMA expression to render

Published in Nature Communications: Revealing the Transcriptomic Drivers of Highly Polyfunctional CAR-T Cells with Bruker Cellular Analysis’ Duomic Technology Read More »

Bruker Cellular Analysis: Driving the Next Wave of Biological Breakthroughs

Announcement /

With the coming together of Berkeley Lights and IsoPlexis, Bruker Cellular Analysis is positioned to power labs across the new frontier of biological and medicinal research. We are uniquely enabling the exploration of the phenome and mastery of single cells for all labs and scientists. Our platform now powers all stages across the discovery and

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