Our best-in-class reagents and chips let you screen plasma cells or memory B cells and find valuable monoclonal antibodies within a week. Feeder-free activation and culture media ensure strong activation of memory B cells and longer secreting plasma cells for reliable results. Choose the right OptoSelect® chips to give you the screening throughput you need for simple or difficult targets. Simplify the recovery of antigen-specific antibody sequences for downstream analysis and development using our Unload and Sanger Prep kits. By using our products, you'll expedite your research and achieve more relevant and effective antibody discoveries in the process.
Product Guide
Feeder-free activation medium ensures strong activation of memory B cells and longer secreting plasma cells for reliable results.
Simplify the recovery of antigen-specific antibody sequences for downstream analysis and development.
Expedite your research and achieve more relevant and effective antibody discoveries.
Workflows with Opto® B
A powerful automated solution for faster, more precise Antibody Discovery
Compatible Instruments:
- Simple to multiplex and/or perform sequential assays
- Automated assay scoring available
- Requires significantly more optimization than in-channel assays
- Manual assay scoring required
- Useful for low secretion rates and/or long assay readout times (e.g. cytotoxicity, reporter gene)
- Memory B cells (750-08323)
- Plasma cells (750-02051)
- Memory B cells (750-08254)
- Plasma cells (750-02050)
- Memory B cells (750-08254)
- ~14,000 NanoPens per chip
- Small pen geometry
- ~11,000 NanoPens per chip
- Larger pen geometry for more robust in-pen assays
- ~20,000 NanoPens per chip
- Larger pen geometry for more robust in-pen assays
Leverage the power and flexibility of single B cell screening to develop your own reagents and workflows for new species, targets, and assays such as cows, chickens, sheeps, goats, and camelids (alpaca, llama).
| Cell | Opto® B Discovery cDNA Synthesis Kit (750-02030) |
| OptoSeq® BCR | OptoSeq® BCR Kit v2 (750-08328) Optional: Extended OptoSeq BCR Bead Unload Kit (750-08097) |
| OptoSeq® Barcoded BCR | OptoSeq® Barcoded BCR Kit (750-01005) Optional: Extended OptoSeq BCR Bead Unload Kit (750-08097) |
| Mouse (Wild Type) | Opto® B Discovery Sanger Prep Kit, Mouse (750-01004) |
| Human | Opto® B Discovery Sanger Prep Kit, Human (750-02041) |
| Rabbit | Opto® B Discovery Sanger Prep Kit, Rabbit (750-08257) |
Unmatched Speed & Efficiency
Antibody Discovery Kit
Your Antibody Discovery Research
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