Datasheet: Live Single Cell Functional Analysis with Beacon Discovery™
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Understand the
Life of Single Cells

Pioneering live single cell, multimodal and temporal functional analysis to accelerate scientific breakthroughs.

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Meet Beacon Discovery™

The most accessible optofluidic platform from Bruker Cellular Analysis. Designed in a compact benchtop format, making function-first, live single-cell research possible for a broader range of academic, translational, and biotech labs.

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Beacon DiscoveryTM Wins The Scientist Top Innovations Award for 2025!

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Beacon DiscoveryTM Wins the Scientist Top Innovators Award for 2025!

From a Single Cell to A World of Discovery

with our innovative Product Suites

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Product Suite
Beacon Optofluidic

Functionally profile live single cells to discover new therapeutic antibodies quickly and efficiently, interrogate T cells and identify novel cell therapies, and compress cell line development timelines while maintaining high quality and productivity.

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Product Suite
Proteomic Barcoding

Capture highly multiplexed cytokine, chemokine, and phosphoprotein signatures from single cells to predict disease progression, treatment resistance, and therapeutic efficacy.

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Discover How
the Cell Analysis
Suite Works

Click below to start your demo experience and explore how workflows and data analysis come together.

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Resource Library

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Transforming Single Cell Analysis Beyond Imagination

Applications across all stages of discovery & development

Discovery/Basic Research

Bioprocessing

Translational Research

Discovery/Basic Research

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Antibody
Discovery

Maximize the success of your antibody discovery campaigns with function-first, high-throughput single B cell screening.

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T Cell
Profiling

Interrogate T cell function to discover effective TCR/CAR sequences and recover cells of interest for multi-omic insights.

Bioprocessing

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Cell Line
Development

Compress cell line development timelines and confidently submit filings to regulators with a reproducible automated workflow.

Translational Research

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Cell Therapy
Development

Translate T cell function to reveal impactful biomarkers that correlate with clinical outcomes.

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Single Cell Proteomics​
Characterization

Comprehensive proteomics profiling of individual cells across a large assay menu of single-cell chip and software products​

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Bulk Proteomics
Characterization

Fully quantitative, high-throughput bulk proteomics

Explore Key Research Areas
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Cancer
Immunology
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Cell & Gene
Therapy
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Infectious
Diseases
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Inflammation & Neurology
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Oncology
 
Customer Spotlights

See how top researchers use our technology to shape the next wave of scientific innovation.

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Anthony Zamora, PhD Assistant Professor, Medical College of Wisconsin
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"We wanted to improve the resolutions of the assays we were using, but one of the challenges we faced is many typical single-cell platforms only provide a one parameter readout…The Beacon is a unique platform that allows me to link everything to a single-cell by looking at multiple parameters."
Dr. Anthony Zamora
Assistant Professor at Medical College of Wisconsin
Molly Shih Manager of Business Development, Mycenax
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"With the Beacon, (Mycenax) offers the next-generation of cell line development platform with shorter timeline and more high-productivity clones."
Molly Shih
Manager of Business Development, Mycenax
Colby A. Souders Chief Scientific Officer, Abveris
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“The main reason why we employ the Beacon system here at Abveris is to enable deep characterization of single B cells in multiple sequential assays. Its design allows for precise control of the movement of cells, leaving you with the ultimate flexibility in assay design and, as a result, a higher screening resolution.”
Colby A. Souders
Chief Scientific Officer, Abveris

Latest Updates

Events View All

Upcoming Seminar
Real-Time Single-Cell Functional Analysis on the Bruker Beacon® Optofluidic System
Date:
Sep 3
Time:
10:00am - 12:00pm
Location:
Headington, Oxford
Region:
England
Date: Sep 3 Time: 10:00am - 12:00pm Location: Headington, Oxford Region: England
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Webinars View All

Optofluidic
Speaker: Vincent Pai, Director, Product Management, Bruker Cellular Analysis | Frances Eun-Hyung Lee, MD, Professor of Medicine, Department of Medicine, Emory Vaccine Center, Emory University
Exploring Long-Lived Plasma Cell BCR Function and Repertoires on Beacon Discovery

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T Cell Biology
Bruker Cellular Analysis and Bruker Spatial Biology systems shown side‑by‑side, illustrating how the Beacon Platform(s) and the CosMx Spatial Molecular Imager work together for linking live T cell function with spatial biology. The left side highlights Beacon capabilities such as single‑cell function, multiple assays per cell, cell‑to‑cell interactions, and dynamic cell behavior over time. The right side highlights CosMx features including subcellular resolution, highest single‑cell plex, same‑cell multiomics, and true spatial context, displayed over layered spatial imaging panels.
February 6, 2026
Linking Live T Cell Function with Spatial Biology for the First Time

Publications View All

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Protocol for isolating antigen-specific monoclonal antibodies from immunized mice utilizing the Beacon platform
Fu M, Wang X, Tang S, Bai S, Ding L, Hu Y, Cao K, Yang T, Zhao C, Zhang X, Xu J, STAR Protocols. 2024.
Speak to a Beacon Expert

Join top biotech, pharma, and academic researchers using Bruker Cellular Analysis to reclaim lab time,
save precious samples, increase efficacy, and cut down therapeutic timelines by a year+.

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