Scientists often use classical immunization strategies and hybridoma technologies to generate antibodies. However, when producing antibodies against poorly immunogenic targets, such as membrane proteins with short extracellular domains, these approaches achieve limited antibody diversity, making it difficult for scientists to select good candidates for pharmaceutical development. Innovative approaches that combine RNA immunization and single cell […]
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Unlock the future of antibody discovery with Opto® B Discovery on the Beacon® platform. This cutting-edge technology streamlines the process, drastically reducing time and cost. This state-of-the-art workflow leverages up to 4 optofluidic chips, characterizing single B cells quickly and efficiently. With the Opto® B Discovery workflow, the Beacon system can significantly speed up your […]
Biotherapeutics comprise a large portion of the treatment options for a wide range of conditions and account for almost half of drugs approvals in 2022. However, the pace of new biologic development has not grown in recent years in part because of the increasing complexity of drug targets and desired performance of these drugs. To […]
With an estimated $12 billion in worldwide sales1, ion channel antibodies are the third best-selling group of prescribed drugs and a huge potential growth area. But the inefficiencies of traditional antibody discovery processes can oftentimes block the road to market approval in early-stage development. Methods such as hybridoma and B cell sequencing comprise multiple manual time-consuming […]
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