IsoCode Chips

Single-Cell
Secretome

Human / Mouse

A fully automated solution for single-cell functional phenotyping of immune cells

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IsoCode Technology

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OVERVIEW

The New Standard in
Single-Cell Functional Biology

The IsoLight and IsoSpark Proteomic Barcoding instruments are hubs for comprehensive functional profiling of each cell type across a large assay menu of single-cell chip and software products. Run an entire highly-multiplexed proteomics workflow. Just add your sample and walk away, achieving fully analyzed data on the same day.

32+ Cytokine Analysis

Multiplexed 32+ cytokine analysis
at single-cell resolution

Functional Phenotyping

Functional Phenotyping targeting
500-1500 single cells per chip

Fully Automated

Fully automated, quick, and
cost-efficient workflow

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Featured Resource

Single-Cell Secretome Product Sheet

Download the Guide

technology workflow

Bruker Cellular Analysis' Innovation in Cellular Analysis: the IsoCode Chip

Our proprietary & patented "Proteomic Barcoded" IsoCode Chip, named the Scientist's number #1 innovation, works by detecting 30+ cytokines per cell, measuring the functional phenotype of each immune cell.

Cytokine Panel

Human Adaptive Immune

Granzyme B, IFN-γ, MIP-1α, Perforin, TNF-α, TNF-β, GM-CSF, IL-2, IL-5, IL-7, IL-8, IL-9, IL-12, IL-15, IL-21, CCL11, IP-10, MIP-1β, RANTES, IL-4, IL-10, IL-13, IL-22, TGFβ1, sCD137, sCD40L, IL-1β, IL-6, IL-17A, IL-17F, MCP-1, MCP-4
Mouse Adaptive Immune

Granzyme B, IFN-γ, MIP-1α, TNF-α, GM-CSF, IL-2, IL-5, IL-7, IL-12p70, IL-15, IL-21, sCD137, CCL11, CXCL1, CXCL13, IP-10, RANTES, Fas, IL-4, IL-10, IL-13, IL-27, TGFβ1, IL-6, IL-17A, MCP-1, IL-1β
Human Natural Killer

Granzyme B, IFN-γ, MIP-1α, Perforin, TNF-α, TNF-β, GM-CSF, IL-2, IL-5, IL-7, IL-8, IL-9, IL-12, IL-15, IL-21, CCL11, IP-10, MIP-1β, RANTES, IL-4, IL-10, IL-13, IL-22, TGFβ1, sCD137, sCD40L, IL-1β, IL-6, IL-17A, IL-17F, MCP-1, MCP-4

Human Innate Immune

IFN-γ, MIP-1α, TNF-α, TNF-β, GM-CSF, IL-8, IL-9, IL-15, IL-18, TGF-α, IL-5, CCL11, IP-10, MIP-1β, RANTES, BCA-1, IL-10, IL-13, IL-22, sCD40L, IL-1β, IL-6, IL-12-p40, IL-12, IL-17A, IL-17F, MCP-1, MCP-4, MIF, EGF, PDGF-BB, VEGF
Human Inflammation

GM-CSF, IFN-γ, IL-2, IL-12, TNF-α, TNF-β, IL-4, IL-5, IL-7, IL-9, IL-13, CCL11, IL-8, IP-10, MCP-1, MCP-4, MIP-1α, MIP-1β, RANTES, IL-10, IL-15, IL-22, TGF-β1, IL-1β, IL-6, IL-17A, IL-17F, IL-21, Granzyme B, Perforin, sCD40L, sCD137
Mouse Innate Immune

IFN-g, TNF-a, MIP-1a, IL-15, GM-CSF, IL-5, IL-10, IL-13, IL-6, IL-17A, MCP-1, IP-10, MIP-1b, EGF, PDGF-BB, MIF

Subset Panels

Membrane Stain

Single-Cell Secretome

A Breakthrough
Technological Innovation

The Single-Cell Adaptive Immune solution measures the "functional phenotype" of each immune cell, allowing for complete single-cell functional characterization. This enables researchers to detect how immune cells proteomically perform against a heterogeneous system, revealing functional biological drivers of persistence, potency, durability and more.

Explore Our Phenome

Case Studies & Research

E-Book

Single-Cell Functional Proteomics Accelerates Immunotherapy Development Opportunities from Pre-Clinical to Clinical Stages

App Note

Reveal sources of Immune Modulation with the Single-Cell Innate Immune solution

Application Highlight

PSI™ Applied to Autoimmune Progression and Precise Therapeutic Targeting

Product Specifications

ISOCODE CHIPS - ISOLIGHT	Product Code
Single-Cell Adaptive Immune Chip - (H) 4	ISOCODE-1001-4
Single-Cell Adaptive Immune Chip - (H) 8	ISOCODE-1001-8
Single-Cell Adaptive Immune Chip - (M) 4	ISOCODE-1004-4
Single-Cell Adaptive Immune Chip - (M) 8	ISOCODE-1004-8
Single-Cell Inflammation Chip - (H) 4	ISOCODE-1003-4
Single-Cell Inflammation Chip - (H) 8	ISOCODE-1003-8
Single-Cell Innate Immune Chip - (H) 4	ISOCODE-3L02-4
Single-Cell Innate Immune Chip - (H) 8	ISOCODE-3L02-8
Single-Cell Innate Immune Chip - (M) 4	ISOCODE-3L04-4
Single-Cell Innate Immune Chip - (M) 8	ISOCODE-3L04-8
Single-Cell Natural Killer Chip - (H) 4	ISOCODE-3L03-4
Single-Cell Natural Killer Chip - (H) 8	ISOCODE-3L03-8

PANELS - ISOLIGHT	Product Code
Single-Cell Adaptive Immune Panel - (H) 4	PANEL-1001-4
Single-Cell Adaptive Immune Panel - (H) 8	PANEL-1001-8
Single-Cell Adaptive Immune Panel - (M) 4	PANEL-1004-4
Single-Cell Adaptive Immune Panel - (M) 8	PANEL-1004-8
Single-Cell Inflammation Panel - (H) 4	PANEL-1003-4
Single-Cell Inflammation Panel - (H) 8	PANEL-1003-8
Single-Cell Innate Immune Panel - (H) 4	PANEL-3L02-4
Single-Cell Innate Immune Panel - (H) 8	PANEL-3L02-8
Single-Cell Innate Immune Panel - (M) 4	PANEL-3L04-4
Single-Cell Innate Immune Panel - (M) 8	PANEL-3L04-8
Single-Cell Natural Killer Panel - (H) 4	PANEL-3L03-4
Single-Cell Natural Killer Panel - (H) 8	PANEL-3L03-8

ISOCODE CHIPS - ISOSPARK	Product Code
Single-Cell Adaptive Immune Chip - (H) 4	ISOCODE-1001-4
Single-Cell Adaptive Immune Chip - (M) 4	ISOCODE-1004-4
Single-Cell Inflammation Chip - (H) 4	ISOCODE-1003-4
Single-Cell Innate Immune Chip - (H) 4	ISOCODE-3L02-4
Single-Cell Innate Immune Chip - (M) 4	ISOCODE-3L04-4
Single-Cell Natural Killer Chip - (H) 4	ISOCODE-3L03-4

PANELS - ISOSPARK	Product Code
Single-Cell Adaptive Immune Panel - (H) 4	S-PANEL-1001-4
Single-Cell Adaptive Immune Panel - (M) 4	S-PANEL-1004-4
Single-Cell Inflammation Panel - (H) 4	S-PANEL-1003-4
Single-Cell Innate Immune Panel - (H) 4	S-PANEL-3L02-4
Single-Cell Innate Immune Panel - (M) 4	S-PANEL-3L04-4
Single-Cell Natural Killer Panel - (H) 4	S-PANEL-3L03-4

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The single-use IsoCode chips are at the core of our technology and required to run our single-cell profiling assays on the fully automated and Award-Winning IsoLight System.

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