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Unravel the Complexity of Single Natural Killer Cell Cytotoxicity and ADCC Mediation

Explore how the Cytotoxicity Assay can be used to characterize and better understand NK cells in the pursuit of more efficacious cell therapies.

What's Inside

In this App Note we discuss:

Directly measure natural killer (NK) cell cytotoxicity at the single-cell level.
Investigate NK cell killing mechanisms and responses to chemical treatment.
Identify NK cell populations that elicit the most robust antibody-dependent cellular cytotoxicity (ADCC) in response to therapeutic monoclonal antibodies.
A Deeper Look

More about this App Note

Single Natural Killer Cell Cytotoxicity and ADCC Mediation

In this application note, we demonstrate how NK cell function can be assessed at the single-cell level using the Opto® Cell Therapy Development workflow on the Bruker Cellular Analysis Platform to characterize both cytotoxicity and ADCC mediation in the presence of target cells. Download to learn more and review the case studies.

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