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Identify and Select Optimal CAR T Cell Phenotypes with the Opto® Cell Therapy Development Workflow

Learn how to combine the T Cell Proliferation Assay with either the Multiplex Cytokine Assay or Cytotoxicity Assay to find your most persistent T cells.

What's Inside

In this App Note we discuss:

Measure antigen-specific proliferation of a single CAR T cell using the T Cell Proliferation Assay.
Combine the T Cell Proliferation Assay with other functional assays to thoroughly characterize CAR T cells.
Correlate information generated using multiple assays to understand the mechanisms that drive optimal T cell behavior.
A Deeper Look

More about this App Note

Identify and Select Optimal CAR T Cell Phenotypes

In this application note, we demonstrate how the T Cell Proliferation Assay and the Multiplex Cytokine Assay in the Opto Cell Therapy Development workflow can be run in combination to identify single T cells that maintain their proliferative ability while secreting one, two, or three cytokines simultaneously. Download to learn more and review the case studies.

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