OVERVIEW
A Next Generation Solution on the Beacon® Platform that Compresses the Cell Line Development Timeline
With the Cell Line Development kit for the Beacon platform, you can select productive, high-quality clones, significantly streamlining your clone selection process compared to traditional methods. Boost your throughput by up to 4 times, while reducing the development timeline by up to 50%, enabling quicker market entry. This translates to cost savings, higher success rates, and shorter timelines for scaling up the top-performing clones.
Product Guide
Supported Instruments
TECHNOLOGY
Cell Line Development Kit
Accelerate cell line development, boosting productivity by up to 4x
Compatible Instruments:
- Target viable, secreting cells in the channel while avoiding dying, non-secretors
- Efficiently clone cells from recently transfected pools to access more genetic diversity
- Highly automated measurement of antibody productivity over several days
- Perform quality assays during the earliest stages of clone selection
PRODUCTS
Build Your Kit
Flexible options in selecting the throughput and measurements you need to evaluate your clones. Choose from 2-chip and 4-chip options depending on your throughput needs. Speak with a BCA representative to help build your kit.
What You Need in Your Kit
Reagents
Assess productivity by assaying monoclonal or bispecific antibodies using reagents that bind to the Fc, Kappa, and/or Lambda domain of the antibody.
Human Fc
- SpotLight™ Human Fc Reagent (520-00024)
- Opto® CLD Kit, Human Fc (750-08126)
- Opto® CLD Kit, Human Fc + Kappa (750-08128)
- SpotLight™ Human Kappa Reagent (520-08018)
- Opto® CLD Kit, Human Kappa (750-08127)
- Opto® CLD Kit, Human Fc + Kappa (750-08128)
- SpotLight™ Human Lambda Reagent (520-08130)
Learn more about the SpotLight™ Reagents for Cell Line Development on the Beacon platform.
Chip Type
Chip type needed for the cell line development workflow.
OptoSelect® 1750b Chip (750-00018)
- ~1,750 NanoPen chambers per chip
- Large pen geometry allows for culturing cells on chip
How to Use Your Kit
Compatible Cell Types
- CHO Cells
Target Molecules Measured
- Traditional mAbs
- Bispecific mAbs
- Other biologics
Assay Types
Traditional antibody therapeutic cell line development with CHO cells
Quality Assays (App Note)
Screen clones for quality attributes, such as insoluble aggregate formation and percent heterodimer for bispecific mAbs
Measure the productivity of clones for biologics that are not traditional mAbs (e.g., vaccines and other proteins)
Order Your Cell Line Development Kit Today
Explore Cell Line
Development Applications
Beacon for Cell Line Development
Unleash the Full Potential of
Your Cell Line Development
Complete the form to connect with us and discover how the Beacon technology can enhance your cell line development programs.
Our expert team will be able to answer your questions, show you how the Beacon system works, and share the most relevant datasheets & case studies for your research.