Light Boxes and Beyond - Maximizing Confidence in Clone Selection Using the Beacon Optofluidic System
Overview
BioPharma Process Research (BPR) at GSK is leading innovation in cell line development by integrating digital tools and automation into clone selection. Traditional cell line identification relies on extensive screening, a time-consuming process that can slow early-phase biopharmaceutical development.
This webinar will showcase how GSK leverages the Beacon Optofluidic System, powered by OptoSelect® technology, to revolutionize cell line selection. Learn how data-driven approaches and novel assays drastically reduces the number of clones that require progression and screening, without compromising the likelihood of success in identifying optimal high product quality clones.
Speakers
Live Webcast Details
Key Takeaway
- Efficient Cell Line Development: Discover how data-driven digital tools and the Bruker Beacon system streamline the identification of optimal cell lines, reducing the need for extensive clone screening while maintaining high success rates.
- Advanced Assays for Complex Molecules: Learn about the novel assays developed for early triage of clonal cell lines, enabling the selection of those expressing correctly formed complex molecules during single-cell cloning.
- Integration of Cutting-edge Technology with Data Analytics: Explore the role of advanced data analytics, including multivariate data analysis and machine learning, in optimizing the cell line development process, backed by extensive automation in data capture and innovative experimental designs.
The Physics and Technology Underlying the Beacon Platform for Cell Line Development
Overview
This session will take a deep dive into the core technology powering the Beacon® platform and its impact on cell line development. We will explore how Optoelectronic Positioning (OEP) technology, AI-based cellular detection, and microfluidic NanoPen® chambers work together to enhance high-precision clone selection—ultimately compressing timelines while improving productivity and quality.
Attendees will gain an understanding of how the Beacon system mimic bioreactor-like conditions and enables multiple sequential assays to assess productivity, stability, and quality attributes with complete automated workflows—all while maintaining FDA-validated monoclonality standards.
Speakers
Live Webcast Details
Key Takeaway
- Compress Cell Line Development Timelines: How the Beacon platform reduces timelines while selecting more productive clones.
- Advanced Clone Selection: Best in class assays to ensure high-performing clone selection.
- Confidently Submit IND Filings to Regulators: How the system delivers superior end to end monoclonality assurance.