A Meta-Analysis of 150+ Antibody Discovery Campaigns: Transgenic Mouse Performance Against Single B Cell Technology Trends
Overview
Twist Biopharma Solutions, a division of Twist Bioscience, is a leading expert in antibody discovery, offering best-in-class in vivo, in vitro, and in silico technologies. With 550+ partnered projects, Twist leverages deep biopharma market insights and cutting-edge engineering platforms to maximize success for even the most difficult campaign targets.
This webinar will present a meta-analysis of over 150 completed single B cell screening campaigns, with a focus on membrane-bound targets. Discover how Twist leverages hyperimmune mice and multi-modal antibody characterization on the Beacon® system to enhance immunization strategies, maximize hit rates for new campaigns, and establish baselines for transgenic models in antibody discovery.
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Key Takeaways
- Best-In-Class Antibody Discovery: Learn how a leading service provider leverages the Beacon® system to optimize antibody hits against challenging targets, including membrane-bound and transmembrane antigens.
- Expertise Through Repeated Success: See how Twist Biopharma Solutions utilizes past campaign performance to optimize immunization strategies and increase success rates.
- Evaluation of Synergistic Platforms: Understand how historical data can validate the use of transgenic mouse models and new host species (e.g., alpaca, rabbit) for antibody discovery.
Strategic Use of Advanced Technologies and Multiple Host Species to Rapidly Generate Cost-Effective Antibody Candidates
Overview
Genovac leverages cutting-edge AI-driven in silico humanization, multi-host species screening, and the Beacon® optofluidic system to accelerate antibody discovery. By integrating diverse immune repertoires and advanced discovery platforms, researchers can enhance lead optimization, increase hit diversity, and improve success rates against difficult targets like RAGE.
This webinar will highlight how Genovac's innovative approach streamlines antibody candidate generation, reduces downstream engineering needs, and improves developability profiles. Discover how wild-type host systems, machine learning in lead optimization, and the Beacon® system work together to drive faster, more efficient therapeutic lead development.
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Key Takeaways
- Enhanced Antibody Discovery with Multiple Host Species: Learn how leveraging diverse immune repertoires across multiple species improves success rates against difficult targets like RAGE.
- AI-Powered Humanization & Lead Optimization: Discover how in silico humanization and machine learning accelerate lead identification and developability, reducing downstream engineering efforts.
- Cutting-Edge Technologies for Faster Antibody Development: Explore how Genovac integrates the Beacon® optofluidic system, wild-type host systems, and advanced discovery platforms to streamline and accelerate antibody discovery and characterization.
Antibody Discovery in 2025: How Industry Leaders are Adapting to Market Trends, Technological Innovations, and Economic Pressures
Overview
The antibody discovery landscape is evolving rapidly, driven by technological breakthroughs, shifting market trends, and economic pressures that challenge traditional workflows. From AI-driven lead optimization and automation to transgenic models and cell-free expression systems, the industry is transforming how therapeutic antibodies are identified and developed.
Join industry leaders from Twist Bioscience and Genovac for an exclusive roundtable discussion on the most pressing trends in antibody discovery, the impact of financial constraints on R&D strategies, and the cutting-edge innovations shaping the future of antibody therapeutics. Learn how companies are adapting to industry shifts, streamlining operations, and maximizing efficiency while driving scientific advancements.
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Key Takeaways
- Industry Trends & Economic Pressures: Gain insights into how leading companies are navigating financial challenges and adapting strategies to optimize discovery pipelines.
- Cutting-Edge Technologies & AI: Explore how automation, AI-driven lead optimization, and transgenic models are transforming therapeutic development.
- The Future of Antibody Discovery: Learn how the Beacon® optofluidic system and other emerging technologies are shaping the next generation of antibody therapeutics.