PUSHING THE BOUNDARIES IN ABD | Webinar 1
A Meta-Analysis of 150+ Antibody Discovery Campaigns: Transgenic Mouse Performance Against Single B Cell Technology Trends
Overview
Twist Biopharma Solutions, a division of Twist Bioscience, is a leading expert in antibody discovery, offering best-in-class in vivo, in vitro, and in silico technologies. With 550+ partnered projects, Twist leverages deep biopharma market insights and cutting-edge engineering platforms to maximize success for even the most difficult campaign targets.
This webinar will present a meta-analysis of over 150 completed single B cell screening campaigns, with a focus on membrane-bound targets. Discover how Twist leverages hyperimmune mice and multi-modal antibody characterization on the Beacon® system to enhance immunization strategies, maximize hit rates for new campaigns, and establish baselines for transgenic models in antibody discovery.
Speakers
Colby Souders, Ph.D.
CSO, Twist Biopharma Solutions
Colby Souders earned his PhD in Cell and Molecular Biology from Texas A&M and previously held positions at Abveris, MassBiologics and Kanyos Bio (now Anokion). At MassBiologics, he worked to advance monoclonal antibodies for the prevention, treatment or diagnosis of various infectious and endogenous diseases, as well as develop related platform technologies to advance and expand the MassBiologics pipeline.
Later, he joined the Kanyos Bio Protein Engineering team to develop therapeutics based on a novel antigen-specific immune tolerance platform. Colby joined Abveris in 2018 as the Chief Scientific Officer to establish best-in-class antibody discovery workflows and build a premium discovery engine with industry-leading timelines. He continues to hold his role as CSO of Twist Biopharma Solutions after Abveris was acquired by Twist Bioscience in 2021.
Vincent Pai
Director of Product Management, Bruker Cellular Analysis
Vincent Pai is Director of Product Management at Bruker Cellular Analysis. He has over 10 years of expertise in cell biology, nanotechnology, and microfluidics, with research experience from UC San Diego and Massachusetts General Hospital in Boston. He joined Berkeley Lights in 2016 and transitioned through roles as an applications engineer, program manager, and product manager. Following Bruker’s acquisition, Vincent now leads new product development for antibody discovery on the Beacon® optofluidic system.
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Live Webcast Details
Key Takeaways
- Best-In-Class Antibody Discovery: Learn how a leading service provider leverages the Beacon® system to optimize antibody hits against challenging targets, including membrane-bound and transmembrane antigens.
- Expertise Through Repeated Success: See how Twist Biopharma Solutions utilizes past campaign performance to optimize immunization strategies and increase success rates.
- Evaluation of Synergistic Platforms: Understand how historical data can validate the use of transgenic mouse models and new host species (e.g., alpaca, rabbit) for antibody discovery.