Dual Axl/MerTK inhibitorINCB081776 creates a proinflammatory tumorimmune microenvironment and enhancesanti-PDL1 efficacy in head and neck cancer. simplomarketing Dual Axl/MerTK inhibitorINCB081776 creates a proinflammatory tumorimmune microenvironment and enhancesanti-PDL1 efficacy in head and neck cancer. Read More »
Immune checkpoint blockade induces gut microbiota translocation that augments extraintestinal antitumor immunity Leave a Comment / simplomarketing Immune checkpoint blockade induces gut microbiota translocation that augments extraintestinal antitumor immunity Read More »
Clinical trials of self-replicating RNA-based cancer vaccines Leave a Comment / simplomarketing Clinical trials of self-replicating RNA-based cancer vaccines Read More »
Immunotoxin-αCD40 therapy activates innate and adaptive immunity and generates a durable antitumor response in glioblastoma models Leave a Comment / simplomarketing Immunotoxin-αCD40 therapy activates innate and adaptive immunity and generates a durable antitumor response in glioblastoma models Read More »
Synapse-tuned CARs enhance immune cell anti-tumor activity Leave a Comment / simplomarketing Synapse-tuned CARs enhance immune cell anti-tumor activity Read More »
Metformin increases natural killer cell functions in head and neck squamous cell carcinoma through CXCL1 inhibition Leave a Comment / simplomarketing Metformin increases natural killer cell functions in head and neck squamous cell carcinoma through CXCL1 inhibition Read More »
First-in-human phase I/II, open-label study of the anti-OX40 agonist INCAGN01949 in patients with advanced solid tumors Leave a Comment / simplomarketing First-in-human phase I/II, open-label study of the anti-OX40 agonist INCAGN01949 in patients with advanced solid tumors Read More »
Effector Memory–Expressing CD45RA (TEMRA) CD8+ T Cells from Kidney Transplant Recipients Exhibit Enhanced Purinergic P2X4 Receptor–Dependent Proinflammatory and Migratory Responses Leave a Comment / simplomarketing Effector Memory–Expressing CD45RA (TEMRA) CD8+ T Cells from Kidney Transplant Recipients Exhibit Enhanced Purinergic P2X4 Receptor–Dependent Proinflammatory and Migratory Responses Read More »
Distinct immune signature predicts progression of vestibular schwannoma and unveils a possible viral etiology Leave a Comment / simplomarketing Distinct immune signature predicts progression of vestibular schwannoma and unveils a possible viral etiology Read More »
Secreted Fas decoys enhance the antitumor activity of engineered and bystander T cells in Fas ligand–expressing solid tumors Leave a Comment / simplomarketing Secreted Fas decoys enhance the antitumor activity of engineered and bystander T cells in Fas ligand–expressing solid tumors Read More »