Discovery, Cloning and Functional Validation of a Neoantigen-specific Patient-derived TCR

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Poster

Discover a method for post-vaccination functional characterization of neoantigen-specific T cells from minimal quantity of patient peripheral blood at the single cell level using a microfluidic device on the Beacon® optofluidic system.

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What's Inside

In this Poster we discuss:

The Opto® Cell Therapy Development 1.0 workflow.

Results and findings.

Surface marker stain, cytokine release and cytotoxicity assay with T cells and dendritic or T2 cells.

Cells recovered through culture process and co-culture events analyzed on the Beacon.

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