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Directly Link T Cell Phenotype and Function to Genotype with the Opto™ Cell Therapy Development 1.0 Workflow

Review use cases for CAR-T cell screening and TCR discovery.

What's Inside

In this App Note we discuss:

Correlate cytokine secretion to target cell killing behavior in CAR-mediated antigen recognition.
Discriminate CAR-T cell subsets based onkinetics of target cell killing.
Link cytokine secretion and target cell killing behavior to TCR sequence in TCR-mediated antigen recognition.
A Deeper Look

More about this App Note

Directly Link T Cell Phenotype and Function to Genotype

In this app note, we demonstrate that the Opto Cell Therapy Development 1.0 workflow on the Lightning system can provide a direct link between T cell phenotype, function, and genotype in the context of different types of T cell based therapeutics. Download to learn more and review the case studies.

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