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Accelerating Internalizing Antibody Discovery with Bruker Cellular Analysis Optofluidic Platforms

Learn how Bruker’s advanced optofluidic systems enables high-throughput functional screening of >10,000 single antibody-secreting B cells to identify rapidly internalizing antibodies targeting PD-L1 to accelerate antibody drug conjugate discovery.

What's Inside

In this Poster we discuss:

Generation of a custom reagent with a pH-sensitive fluorescent dye for a new internalizing antibody assay design.
A case study on screening for rapidly internalizing rabbit antibodies specific to surface-expressed PD-L1.
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