Next-Level T Cell Analysis: Discovering Function, Biomarkers, and Therapeutic Potential

Part 1: Revolutionizing Functional Immune Cell Screening and Therapy Development with the Beacon Platform

Explore how the innovative Beacon platform allows researchers to set up thousands of parallel live single-cell experiments to gain a deep understanding of cellular heterogeneity and functionality. Simultaneously characterize dynamic cytotoxicity, cytokine secretion, and surface marker expression on the same single cell to understand behavioral relationships. Afterward, recover and export T cells of interest to generate multiomic insights (TCR-seq and mRNA-seq) and uncover the genetic drivers of functionality. The Beacon provides exceptional control of single T cells enabling researchers to accelerate target and therapeutic discovery, confirm and validate cellular performance, and reveal deep, multifaceted biomarkers.

Part 2: Best Practices for Setting Up and Running Automated T Cell Workflows on Bruker’s Beacon Instruments

Gain hands-on insights into how automated workflows are designed, executed, and analyzed on the Beacon platform. Discover how Opto Electro Positioning (OEP), microfluidic technology and machine learning-based cellular detection allow for seamless single-cell culture and assay integration.