Hypoxia-responsive CAR-T cells exhibit reduced exhaustion and enhanced efficacy in solid tumors John Williams Hypoxia-responsive CAR-T cells exhibit reduced exhaustion and enhanced efficacy in solid tumors Read More »
Exploiting the CD200-CD200R Immune Checkpoint Axis in Multiple Myeloma to Enhance CAR-T Therapy John Williams Exploiting the CD200-CD200R Immune Checkpoint Axis in Multiple Myeloma to Enhance CAR-T Therapy Read More »
Alpaca single B cell interrogation and heavy-chain-only antibody discovery on an optofluidic platform John Williams Alpaca single B cell interrogation and heavy-chain-only antibody discovery on an optofluidic platform Read More »
Multiomics and spatial mapping characterizes human CD8+ T cell states in cancer John Williams Multiomics and spatial mapping characterizes human CD8+ T cell states in cancer Read More »
Potent Omicron-neutralizing antibodies isolated from a patient vaccinated 6 months before Omicron emergence John Williams Potent Omicron-neutralizing antibodies isolated from a patient vaccinated 6 months before Omicron emergence Read More »
The IgG4 hinge with CD28 transmembrane domain improves VHH-based CAR T cells targeting a membrane-distal epitope of GPC1 in pancreatic cancer John Williams The IgG4 hinge with CD28 transmembrane domain improves VHH-based CAR T cells targeting a membrane-distal epitope of GPC1 in pancreatic cancer Read More »
Dual Axl/MerTK inhibitorINCB081776 creates a proinflammatory tumorimmune microenvironment and enhancesanti-PDL1 efficacy in head and neck cancer. simplomarketing Dual Axl/MerTK inhibitorINCB081776 creates a proinflammatory tumorimmune microenvironment and enhancesanti-PDL1 efficacy in head and neck cancer. Read More »
Immune checkpoint blockade induces gut microbiota translocation that augments extraintestinal antitumor immunity Leave a Comment / simplomarketing Immune checkpoint blockade induces gut microbiota translocation that augments extraintestinal antitumor immunity Read More »
Clinical trials of self-replicating RNA-based cancer vaccines Leave a Comment / simplomarketing Clinical trials of self-replicating RNA-based cancer vaccines Read More »
Immunotoxin-αCD40 therapy activates innate and adaptive immunity and generates a durable antitumor response in glioblastoma models Leave a Comment / simplomarketing Immunotoxin-αCD40 therapy activates innate and adaptive immunity and generates a durable antitumor response in glioblastoma models Read More »