Research Area

Bruker Cellular Analysis' precision development and pathway monitoring are advancing targeting in Oncology

Use true functional immune cell biology to reveal biomarkers for autoimmunity and immune-related adverse events.

Oncology

Accelerate Research with Bruker Cellular Analysis

Discover sources of resistance to Cancer Signaling Pathway therapies by understanding single-cell pathways that translate to therapeutic insights

Bruker Cellular Analysis detects the key intracellular pathways in tumor cells that can uncover critical and unseen targets in oncology, helping you understand earlier in development the impacts of your therapies, and also mechanisms behind patient resistance in oncology research.

FEATURED WEBINAR

Cancer Resistance Revealed Through the Single Cell Intracellular Proteome, Masked Through Bulk and Genomics

Watch the Video

Webinars & Interviews

See how industry leaders and pioneers are revealing the true functional biology to accelerate research and medicine

Proteomics

Speaker: Arnold Levine, PhD, Professor Emeritus, Simons Center for Systems Biology, Institute for Advanced Study

The Structure and Functions of the p53 Pathway: Information Acquisition, Redundancy, and Connectivity

Proteomics

Speaker: Denis Wirtz, PhD, Vice Provost for Research, Chemical & Biomolecular Engineering, Pathology, Oncology Director, Johns Hopkins Physical Sciences-Oncology Center Johns Hopkins University and Johns Hopkins School of Medicine

Understanding Cancer Cell Communication to Infer a Strategy to Inhibit Tumor Cell Migration

Proteomics

Speaker: Rui Zheng, PhD, VP of Innovations, Bruker Cellular Analysis

Cancer Resistance Revealed through the Single-Cell Intracellular Proteome, Masked through Bulk & Genomics

Publications

Publications highlight customer breakthroughs across research and medicine.

Single-Cell Phosphoproteomics Resolves Adaptive Signaling Dynamics and Informs Targeted Combination Therapy in Glioblastoma.

Wei W et al., Cancer Cell, 29:4 563-573 2016.

JAK-STAT Pathway Activation in Malignant and Non-Malignant Cells Contributes to MPN Pathogenesis and Therapeutic Response.

Kleppe M et al., Cancer Discovery, 5 (3), 316-31 2015.

Chemical Methods for the Simultaneous Quantitation of Metabolites and Proteins from Single Cells.

Xue M et al., Journal of the American Chemical Society, 137 (12), 4066–4069 2015.

Glioblastoma Cellular Architectures are Predicted Through the Characterization Of Two-Cell Interactions.

Kravchenko-Balasha N et al., Proc. Natl. Acad. Sci., 111, 6521- 26 2014.

Bruker Cellular Analysis' Functional Cell Biology Has Been Published in 100+ Publications

Case Studies and Resources

Stay at the cutting edge of science and medicine with case studies, literature and resources

App Note

Proteomic Barcoding Product Suite for Oncology & Tumor Functional Phenotyping

View Resource