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1 - 25 of 197 Publications
Cellular and Regenerative Medicine
Phase I/II Study of Adaptive Manufactured Lentiviral Anti-CD20/Anti-CD19 Chimeric Antigen Receptor T Cells for Relapsed, Refractory Mantle Cell Lymphoma
Nirav N. Shah, MD, MS, Alfredo S. Colina, BA, Bryon D. Johnson, PhD, Aniko Szabo, PhD, Fateeha Furqan, MD, Tyce Kearl, MD, PhD, Dina Schneider, PhD, Marlenny Vargas-Cortes, BS, Jessica L. Schmeling, BS, Michael B. Dwinell, PhD, Katie Palen, BS, Walter Longo, MD, Peiman Hematti, MD, Anthony E. Zamora, PhD, Parameswaran Hari, MD, M, Daniel Bucklan, MD, Ashley Cunningham, MD, Mehdi Hamadani, MD, and Timothy S. Fenske, MD . Journal of Clinical Oncology. 2025.
T Cell Profiling
Cross-reactive sarbecovirus antibodies induced by mosaic RBD-nanoparticles
Chengcheng Fan, Jennifer R. Keeffe, Kathryn E. Malecek, Alexander A. Cohen, Anthony P. West Jr., Viren A. Baharani, Annie V. Rorick, Han Gao, Priyanthi N.P. Gnanapragasam, Semi Rho, Jaasiel Alvarez, Luisa N. Segovia, Theodora Hatziioannou, Paul D. Bieniasz, Pamela J. Bjorkman. bioRxiv. 2025.
Immunology
Interleukin-27-polarized HIV-resistant M2 macrophages are a novel subtype of macrophages that express distinct antiviral gene profiles in individual cells: implication for the antiviral effect via different mechanisms in the individual cell-dependent manner
Imamichi, T; Yang, J; Chen, Q; Goswami, S; Marquez, M; Kariyawasam, U; Sharma, HN; Wiscovitch-Russo, R; Li, X; Aioi, A; Adelsberger, JW; Chang, W; Higgins, J; Sui, H;. Frontiers in Immunology. 2025.
Cellular and Regenerative Medicine
A Proteomics Outlook on the Molecular Effectors of CAR-T Cell Therapy in Cancer Management
Teibo, JO; Picanรงo-Castro, V; de Souza, LEB; Faรงa, VM. Journal of Proteome Research. 2025.
Oncology
A novel anti-HER2/EGFR bispecific antibody-drug conjugate demonstrates promising antitumor efficacy and overcomes resistance to HER2- or EGFR-targeted ADCs
Huang, H; Zhou, Y; Shang, C; Zhang, Y; Shen, Y. Springer Nature: Investigational New Drugs. 2025.
Oncology
ZP4: A novel target for CAR-T cell therapy in triple negative breast cancer
Somes, LK; Lei, JT; Yi, X; Chamorro, DF; Shafer, P; Gad, AZ; Dobrolecki, LE; Madaras, E; Ahmed, N; Lewis, MT; Zhang, B; Hoyos, V. Molecular Therapy: the journal of the American Society of Gene Therapy. 2025.
Oncology
Loss of LDOC1 by chromatin compaction in mesenchymal tumor cells is required for PFA1 ependymoma growth
de Sousa, GR; Calzadilla, AJ; Grimaldo, E; Donson, AM; Sobral, LM; Jones, KM; Liu, T; Amani, V; Venkataraman, S; Dahl, NA; Levy, JMM; Phang, T; Vibhakar, R; Hankinson, T; Handler, M; Valera, ET; Foreman, NK; Griesinger, AM. Neuro-oncology. 2025.
Cancer Immunology
Single-Cell CD4 and CD8 T-Cell Secretome Profiling Reveals Temporal and Niche Differences in Acute Myeloid Leukemia Following Immune Checkpoint Blockade Therapy
Root JL, Desai PN, Ly C, Wang B, Jelloul FZ, Zhou J, Mackay S, Alfayez M, Matthews J, Pierce S, Reville PK, Daver N, Abbas HA. Cancer Research Communications. 2024.
Immunology
Polyfunctional T cells and unique cytokine clusters imprint the anti rAAV2/rAAV9 vector immune response
Holtkamp SJ, Lagoda FR, Lister A, Harish P, Kleymann U, Pesch T, Soon CF, Pirmohamed M, Naisbitt D, Trautwein M. Frontiers in Immunology. 2024.
Vaccines & Infectious Disease
High-throughput single-cell analysis reveals Omp38-specific monoclonal antibodies that protect against Acinetobacter baumannii infection
Zhang Y, Cheng H, Yu P, Wang S, Dong H, Lu S, Yang R, Li B, Luo J, Mao R, Zhang Z, Qi Y, Chen X, Ding J, He Z, Zhang J, Zhao T, Chen X, Lin R, Li H, Tian Y, Wu Y. Emerging Microbes & Infections. 2025.
Cancer Immunology
NK Receptor Signaling Lowers TCR Activation Threshold, Enhancing Selective Recognition of Cancer Cells by TAA-Specific CTLs
Dong B, Obermajer N, Tsuji T, Matsuzaki J, Bonura CM, Sander C, Withers H, Long MD, Chavel C, Olejniczak SH, Minderman H, Kirkwood JM, Edwards RP, Storkus WJ, Romero P, Kalinski P. Cancer Immunology Research. 2024.
Cancer Immunology
Nanomaterial-Mediated Delivery of MLKL Plasmids Sensitizes Tumors to Immunotherapy and Reduces Metastases
Chu T, Maksoudian C, Pedrotti S, Izci M, Perez Gilabert I, Koutsoumpou X, Sargsian A, Girmatsion H, Roque Goncalves F, Scheele CLGJ, Manshian BB, Soenen SJ. Advanced Healthcare Materials. 2024.
Cancer Immunology
Intratumoral radiation dose heterogeneity augments antitumor immunity in mice and primes responses to checkpoint blockade
Jagodinsky JC, Vera JM, Jin WJ, Shea AG, Clark PA, Sriramaneni RN, Havighurst TC, Chakravarthy I, Allawi RH, Kim K, Harari PM, Sondel PM, Newton MA, Crittenden MR, Gough MJ, Miller JR, Ong IM, Morris ZS. Science Translational Medicine. 2024.
Cellular and Regenerative Medicine
Single-cell CAR T atlas reveals type 2 function in 8-year leukaemia remission
Bai Z, Feng B, McClory SE, Coutinho de Oliveira B, Diorio C, Gregoire C, Tao B, Yang L, Zhao Z, Peng L, Sferruzza G, Zhou L, Zhou X, Kerr J, Baysoy A, Su G, Yang M, Camara PG, Chen S, Tang L, June CH, Melenhorst JJ, Grupp SA, Fan R. Nature. 2024.
Immunology
Dimethyl Fumarate attenuates synovial inflammation, reduces nociception, and inhibits the development of post-traumatic osteoarthritis
Khan, NM; Kaiser, JM; Chihab, S;Eng, T; Drissi, H. Biomedicine & Pharmacotherapy. 2025.
Oncology
Bile acid synthesis impedes tumor-specific T cell responses during liver cancer
Varanasi, SK; Chen, D; Liu, Y; Johnson, MA; Miller, CM; Ganguly, S; Lande, K; LaPorta, MA; Hoffmann, FA; Mann, TH; Teneche, MG; Casillas, E; Mangalhara, KC; Mathew, V; Sun, M; Jensen, IJ; Farsakoglu, Y; Chen, T; Parisi, B; Deota, S; Havas, A; Lee, J; Chung, HK; Schietinger, A; Panda, S; Williams, AE; Farber, DL; Dhar, D; Adams, PD; Feng, GS; Shadel, GS; Sundrud, MS; Kaech, SM. Science. 2025.
Antibody Discovery, Vaccines & Infectious Disease
Protective antibodies target cryptic epitope unmasked by cleavage of malaria sporozoite protein
Dacon, C; Moskovitz, R; Swearingen, K; Da Silva Pereira, L; Flores-Garcia, Y; Aleshnick, M; Kanatani, S; Flynn, B; Molina-Cruz, A; Wollenberg, K; Traver, M; Kirtley, P; Purser, L; Dillon, M; Bonilla, B; Franco, A; Petros, S; Kritzberg, J; Tucker, C; Paez, GG; Gupta, P; Shears, MJ; Pazzi, J; Edgar, JM; Teng, AA; Belmonte, A; Oda, K; Doumbo, S; Krymskaya, L; Skinner, J; Li, S; Ghosal, S; Kayentao, K; Ongoiba, A; Vaughan, A; Campo, JJ; Traore, B; Barillas-Mury, C; Wijayalath, W; Idris, A; Crompton, PD; Sinnis, P; Wilder, BK; Zavala, F; Seder, RA; Wilson, IA; Tan, J. Science. 2025.
Immunology
IL-23 tunes inflammatory functions of human mucosal-associated invariant T (MAIT) cells
Camard, L; Stephen, T; Yahia-Cherbal, H; Guillemot, V; Mella, S; Baillet, V; Lopez-Maestre, H; Capocefalo, D; Cantini, L; Leloup, C; Marsande, J; Garro, K; Bailo, J; Dangien, A; Pietrosemoli, N; Hasan, M; Wang, H; Eckle, S; Fourie, A; Greving, C; Shaikh, B; Parker, R; Cua, D; Bianchi, E; Rogge, L. iScience. 2025.
Cancer Immunology
Quantitative peripheral live single T-cell dynamic polyfunctionality profiling predicts lung cancer checkpoint immunotherapy treatment response and clinical outcomes
Lim, ZF; Wu, X; Zhu, L; Albandar, H; Hafez, M; Zhao, C; Almubarak, M; Smolkin, M; Zheng, H; Wen, S; Ma, PC. Translational Lung Cancer Research. 2024.
Cellular and Regenerative Medicine
Interleukin-15-armoured GPC3 CAR T cells for patients with solid cancers
Steffin, D; Ghatwai, N; Montalbano, A; Rathi, P; Courtney, A; Arnett, A; Fleurence, J; Sweidan, R; Wang, T; Zhang, H; Masand, P; Maris, J; Martรญnez, D; Pogoriler, J; Varadarajan, N; Thakkar, S; Lyon, D; Lapteva, N; Mei, Z; Patel, K; Lรณpezโ€Terrada, D; Ramos, C; Lulla, P; Armaghany, T; Grilley, B; Gottschalk, S; Dotti, G; Metelitsa, L; Heslop, H; Brenner, M; Sumazin, P; Heczey, A. Carolina Digital Repository. 2024.
Cell Line Development
SiMPl-GS: Advancing Cell Line Development via Synthetic Selection Marker for Next-Generation Biopharmaceutical Production
Yoon C, Lee E, Kim D, Joung S, Kim Y, Jung H, Kim YG, Lee GM. Advanced Science. 2024.
Cellular and Regenerative Medicine
CD28 Costimulation Augments CAR Signaling in NK Cells via the LCK/CD3ฮถ/ZAP70 Signaling Axis
Acharya S, Basar R, Daher M, Rafei H, Li P, Uprety N, Ensley E, Shanley M, Kumar B, Banerjee PP, Garcia LM, Lin P, Mohanty V, Kim KH, Jiang X, Pan Y, Li Y, Liu B, Nunez Cortes AK, Zhang C, Fathi M, Rezvan A, Montalvo MJ, Cha SL, Reyes-Silva F, Shrestha R, Guo X, Kundu K, Biederstรคdt A, Muniz-Feliciano L, Deyter GM, Kaplan M, Jiang XR, Liu E, Jain A, Roszik J, Fowlkes NW, Solis Soto LM, Raso MG, Khoury JD, Lin P, Vega F, Varadarajan N, Chen K, Marin D, Shpall EJ, Rezvani K. Cancer Discovery. 2024.
Antibody Discovery
Protocol for isolating antigen-specific monoclonal antibodies from immunized mice utilizing the Beacon platform
Fu M, Wang X, Tang S, Bai S, Ding L, Hu Y, Cao K, Yang T, Zhao C, Zhang X, Xu J. STAR Protocols. 2024.
Cancer Immunology, Cellular and Regenerative Medicine
Cell therapy using ex vivo reprogrammed macrophages enhances antitumor immune responses in melanoma
Noonepalle SKR, Gracia-Hernandez M, Aghdam N, Berrigan M, Coulibaly H, Li X, Zevallos-Delgado C, Pletcher A, Weselman B, Palmer E, Knox T, Sotomayor E, Chiappinelli KB, Wardrop D, Horvath A, Shook BA, Lee N, Dritschilo A, Fernandes R, Musunuri K, Shibata M, Villagra A. Journal of Experimental & Clinical Cancer Research. 2024.
Stem cells
Dipeptidyl peptidase-4 marks distinct subtypes of human adipose stromal/stem cells with diferent hepatocyte diferentiation and immunoregulatory properties
Zhang Y, Hua M, Ma X, Li W, Cao Y, Han X, Huang X, Zhang H. Stem Cell Research & Therapy. 2024.