AKT inhibition generates potent polyfunctional clinical grade AUTO1 CAR T-cells, enhancing function and survival John Williams AKT inhibition generates potent polyfunctional clinical grade AUTO1 CAR T-cells, enhancing function and survival Read More »
Infusion Product TNFα, Th2, and STAT3 Activities Are Associated with Clinical Responses to Transgenic T-cell Receptor Cell Therapy John Williams Infusion Product TNFα, Th2, and STAT3 Activities Are Associated with Clinical Responses to Transgenic T-cell Receptor Cell Therapy Read More »
Novel mesothelin-targeted chimeric antigen receptor-modified UNKT cells are highly effective in inhibiting tumor progression John Williams Novel mesothelin-targeted chimeric antigen receptor-modified UNKT cells are highly effective in inhibiting tumor progression Read More »
Hypoxia-responsive CAR-T cells exhibit reduced exhaustion and enhanced efficacy in solid tumors John Williams Hypoxia-responsive CAR-T cells exhibit reduced exhaustion and enhanced efficacy in solid tumors Read More »
Exploiting the CD200-CD200R Immune Checkpoint Axis in Multiple Myeloma to Enhance CAR-T Therapy John Williams Exploiting the CD200-CD200R Immune Checkpoint Axis in Multiple Myeloma to Enhance CAR-T Therapy Read More »
Multiomics and spatial mapping characterizes human CD8+ T cell states in cancer John Williams Multiomics and spatial mapping characterizes human CD8+ T cell states in cancer Read More »
The IgG4 hinge with CD28 transmembrane domain improves VHH-based CAR T cells targeting a membrane-distal epitope of GPC1 in pancreatic cancer John Williams The IgG4 hinge with CD28 transmembrane domain improves VHH-based CAR T cells targeting a membrane-distal epitope of GPC1 in pancreatic cancer Read More »
Dual Axl/MerTK inhibitorINCB081776 creates a proinflammatory tumorimmune microenvironment and enhancesanti-PDL1 efficacy in head and neck cancer. simplomarketing Dual Axl/MerTK inhibitorINCB081776 creates a proinflammatory tumorimmune microenvironment and enhancesanti-PDL1 efficacy in head and neck cancer. Read More »
Immune checkpoint blockade induces gut microbiota translocation that augments extraintestinal antitumor immunity Leave a Comment / simplomarketing Immune checkpoint blockade induces gut microbiota translocation that augments extraintestinal antitumor immunity Read More »
Clinical trials of self-replicating RNA-based cancer vaccines Leave a Comment / simplomarketing Clinical trials of self-replicating RNA-based cancer vaccines Read More »
