Secreted Fas decoys enhance the antitumor activity of engineered and bystander T cells in Fas ligand–expressing solid tumors Leave a Comment / simplomarketing Secreted Fas decoys enhance the antitumor activity of engineered and bystander T cells in Fas ligand–expressing solid tumors Read More »
Inhibition of integrin αVβ3 signaling improves the antineoplastic effect of bexarotene in cutaneous T-cell lymphoma Leave a Comment / simplomarketing Inhibition of integrin αVβ3 signaling improves the antineoplastic effect of bexarotene in cutaneous T-cell lymphoma Read More »
Transgenic expression of IL-7 regulates CAR-T cell metabolism and enhances in vivo persistence against tumor cells Leave a Comment / simplomarketing Transgenic expression of IL-7 regulates CAR-T cell metabolism and enhances in vivo persistence against tumor cells Read More »
A long-acting interleukin-7, rhIL-7-hyFc, enhances CAR T cell expansion, persistence, and anti-tumor activity Leave a Comment / simplomarketing A long-acting interleukin-7, rhIL-7-hyFc, enhances CAR T cell expansion, persistence, and anti-tumor activity Read More »
Single-cell antigen-specific landscape of CAR T infusion product identifies determinants of CD19-positive relapse in patients with ALL Leave a Comment / simplomarketing Single-cell antigen-specific landscape of CAR T infusion product identifies determinants of CD19-positive relapse in patients with ALL Read More »
Enabling Allogeneic T Cell-Based Therapies: Scalable Stirred-Tank Bioreactor Mediated Manufacturing Leave a Comment / simplomarketing Enabling Allogeneic T Cell-Based Therapies: Scalable Stirred-Tank Bioreactor Mediated Manufacturing Read More »
Bispecific targeting of CD20 and CD19 increases polyfunctionality of chimeric antigen receptor T-cell products in B-cell malignancies Leave a Comment / simplomarketing Bispecific targeting of CD20 and CD19 increases polyfunctionality of chimeric antigen receptor T-cell products in B-cell malignancies Read More »
Cytosine Base Editing Enables Quadruple-Edited Allogeneic CAR-T Cells for T-ALL Leave a Comment / simplomarketing Cytosine Base Editing Enables Quadruple-Edited Allogeneic CAR-T Cells for T-ALL Read More »
Transgenic Expression of IL15 Retains CD123-Redirected T Cells in a Less Differentiated State Resulting in Improved Anti-AML Activity in Autologous AML PDX Models Leave a Comment / simplomarketing Transgenic Expression of IL15 Retains CD123-Redirected T Cells in a Less Differentiated State Resulting in Improved Anti-AML Activity in Autologous AML PDX Models Read More »
CCL22 mutations drive natural killer cell lymphoproliferative disease by deregulating microenvironmental crosstalk Leave a Comment / simplomarketing CCL22 mutations drive natural killer cell lymphoproliferative disease by deregulating microenvironmental crosstalk Read More »